{"id":22873,"date":"2023-11-17T12:05:21","date_gmt":"2023-11-17T11:05:21","guid":{"rendered":"https:\/\/transfer.pk.edu.pl\/?post_type=oferta-tech&p=22873"},"modified":"2024-03-19T07:59:28","modified_gmt":"2024-03-19T06:59:28","slug":"nietoksyczne-nosniki-leczniczych-substancji-czynnych-na-bazie-nanomaterialow","status":"publish","type":"oferta-tech","link":"https:\/\/transfer.pk.edu.pl\/en\/oferta-tech\/nietoksyczne-nosniki-leczniczych-substancji-czynnych-na-bazie-nanomaterialow\/","title":{"rendered":"Nietoksyczne no\u015bniki leczniczych substancji czynnych na bazie nanomateria\u0142\u00f3w"},"content":{"rendered":"\n
\n
\n

Kierownik projektu:<\/strong>
dr hab. in\u017c. Jolanta Pulit-Prociak<\/p>\n\n\n\n

Technologia wytwarzania nowoczesnych no\u015bnik\u00f3w \u015brodk\u00f3w terapeutycznych. No\u015bniki wytwarzane s\u0105 na bazie nanocz\u0105stek tlenku cynku lub tlenku tytanu (IV) poprzez osadzenie na ich powierzchni substancji organicznej wybranej z grupy peptyd\u00f3w lub aldoheksoz. Materia\u0142y te znajduj\u0105 zastosowanie jako systemy dostarczania lek\u00f3w, a dzi\u0119ki obecno\u015bci na ich powierzchni substancji organicznej, charakteryzuj\u0105 si\u0119 one zmniejszon\u0105 toksyczno\u015bci\u0105 wzgl\u0119dem organizm\u00f3w \u017cywych, w por\u00f3wnaniu do materia\u0142\u00f3w niezmodyfikowanych.<\/p>\n<\/div>\n\n\n\n

\n
\"\"<\/figure>\n<\/div>\n<\/div>\n\n\n\n


No\u015bniki charakteryzuj\u0105 si\u0119 te\u017c uwalnianiem substancji aktywnej w spos\u00f3b sta\u0142y w badanym przedziale czasowym. Aplikacja substancji leczniczych w proponowanej formie spowoduje uproszczenie schematu leczenia. Kontrolowane uwalnianie leku nie wymaga bowiem zwi\u0119kszenia dawki oraz cz\u0119stotliwo\u015bci podawania leku potrzebnych do uzyskania efektu to\u017csamego z rezultatem stosowania leku o natychmiastowym uwalnianiu. Wp\u0142ywa to r\u00f3wnie\u017c na popraw\u0119 profilu tolerancji pacjenta na lek oraz ograniczenie wyst\u0105pienia i minimalizuje nast\u0119pstwa powik\u0142a\u0144 post-farmakologicznych. Mo\u017cliwo\u015b\u0107 zastosowania w terapiach iniekcyjnych, doustnych, podsk\u00f3rnych i innych.<\/p>\n\n\n\n

Um\u00f3w si\u0119 na indywidualne spotkanie z tw\u00f3rcami: 
e-mail: s2b@transfer.pk.edu.pl<\/a>,
tel.: 12 628 28 45<\/p>\n","protected":false},"excerpt":{"rendered":"

[…]<\/p>\n","protected":false},"author":925,"featured_media":22876,"parent":0,"template":"","meta":{"_acf_changed":false,"inline_featured_image":false,"_uag_custom_page_level_css":"","site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}}},"kategoria-oferty-technologicznej":[],"slowo-kluczowe":[97,106,94,109],"class_list":["post-22873","oferta-tech","type-oferta-tech","status-publish","has-post-thumbnail","hentry","slowo-kluczowe-materialy-funkcjonalne","slowo-kluczowe-nanomaterialy","slowo-kluczowe-nanotechnologia","slowo-kluczowe-systemy-transportujace"],"acf":[],"uagb_featured_image_src":{"full":["https:\/\/transfer.pk.edu.pl\/wp-content\/uploads\/2023\/11\/32-chemia-medyczna-1.jpg",200,200,false],"thumbnail":["https:\/\/transfer.pk.edu.pl\/wp-content\/uploads\/2023\/11\/32-chemia-medyczna-1-150x150.jpg",150,150,true],"medium":["https:\/\/transfer.pk.edu.pl\/wp-content\/uploads\/2023\/11\/32-chemia-medyczna-1.jpg",200,200,false],"medium_large":["https:\/\/transfer.pk.edu.pl\/wp-content\/uploads\/2023\/11\/32-chemia-medyczna-1.jpg",200,200,false],"large":["https:\/\/transfer.pk.edu.pl\/wp-content\/uploads\/2023\/11\/32-chemia-medyczna-1.jpg",200,200,false],"thumblist":["https:\/\/transfer.pk.edu.pl\/wp-content\/uploads\/2023\/11\/32-chemia-medyczna-1.jpg",200,200,false],"thumbrelated":["https:\/\/transfer.pk.edu.pl\/wp-content\/uploads\/2023\/11\/32-chemia-medyczna-1.jpg",200,200,false],"meccarouselthumb":["https:\/\/transfer.pk.edu.pl\/wp-content\/uploads\/2023\/11\/32-chemia-medyczna-1.jpg",200,200,false],"gridsquare":["https:\/\/transfer.pk.edu.pl\/wp-content\/uploads\/2023\/11\/32-chemia-medyczna-1.jpg",200,200,false],"tileview":["https:\/\/transfer.pk.edu.pl\/wp-content\/uploads\/2023\/11\/32-chemia-medyczna-1.jpg",200,200,false],"1536x1536":["https:\/\/transfer.pk.edu.pl\/wp-content\/uploads\/2023\/11\/32-chemia-medyczna-1.jpg",200,200,false],"2048x2048":["https:\/\/transfer.pk.edu.pl\/wp-content\/uploads\/2023\/11\/32-chemia-medyczna-1.jpg",200,200,false]},"uagb_author_info":{"display_name":"dkluczynski","author_link":"https:\/\/transfer.pk.edu.pl\/en\/author\/dkluczynski\/"},"uagb_comment_info":0,"uagb_excerpt":"[…]","_links":{"self":[{"href":"https:\/\/transfer.pk.edu.pl\/en\/wp-json\/wp\/v2\/oferta-tech\/22873","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/transfer.pk.edu.pl\/en\/wp-json\/wp\/v2\/oferta-tech"}],"about":[{"href":"https:\/\/transfer.pk.edu.pl\/en\/wp-json\/wp\/v2\/types\/oferta-tech"}],"author":[{"embeddable":true,"href":"https:\/\/transfer.pk.edu.pl\/en\/wp-json\/wp\/v2\/users\/925"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/transfer.pk.edu.pl\/en\/wp-json\/wp\/v2\/media\/22876"}],"wp:attachment":[{"href":"https:\/\/transfer.pk.edu.pl\/en\/wp-json\/wp\/v2\/media?parent=22873"}],"wp:term":[{"taxonomy":"kategoria-oferty-technologicznej","embeddable":true,"href":"https:\/\/transfer.pk.edu.pl\/en\/wp-json\/wp\/v2\/kategoria-oferty-technologicznej?post=22873"},{"taxonomy":"slowo-kluczowe","embeddable":true,"href":"https:\/\/transfer.pk.edu.pl\/en\/wp-json\/wp\/v2\/slowo-kluczowe?post=22873"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}